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Vladimir P Skulachev Selected Research

Plastoquinone

1/2019The single intravenous administration of mitochondria-targeted antioxidant SkQR1 after traumatic brain injury attenuates neurological deficit in rats.
7/2018Neuroprotective Effects of Mitochondria-Targeted Plastoquinone in a Rat Model of Neonatal Hypoxic⁻Ischemic Brain Injury.
8/2015Neuroprotective Effects of Mitochondria-Targeted Plastoquinone and Thymoquinone in a Rat Model of Brain Ischemia/Reperfusion Injury.
1/2015Radioprotective effects of mitochondria-targeted antioxidant SkQR1.
1/2013Mitochondria-targeted plastoquinone antioxidant SkQ1 prevents amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices.
8/2012Effect of liposomes on energy-dependent uptake of the antioxidant SkQR1 by isolated mitochondria.
1/2012The mitochondria-targeted antioxidants and remote kidney preconditioning ameliorate brain damage through kidney-to-brain cross-talk.
2/2010Mitochondria-targeted antioxidant SkQR1 selectively protects MDR (Pgp 170)-negative cells against oxidative stress.

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Vladimir P Skulachev Research Topics

Disease

4Neoplasms (Cancer)
01/2020 - 01/2010
4Wounds and Injuries (Trauma)
01/2019 - 05/2015
4Stroke (Strokes)
07/2018 - 04/2005
4Body Weight (Weight, Body)
01/2017 - 01/2013
3Mitochondrial Diseases (Mitochondrial Disease)
07/2018 - 01/2015
3Alzheimer Disease (Alzheimer's Disease)
12/2016 - 01/2012
2Inflammation (Inflammations)
06/2019 - 01/2017
2Sepsis (Septicemia)
06/2019 - 01/2017
2Brain Ischemia (Cerebral Ischemia)
12/2016 - 08/2015
2Ischemia
12/2016 - 08/2012
2Glaucoma
01/2015 - 05/2009
2Necrosis
05/2009 - 05/2006
1Poisoning
01/2020
1Neonatal Sepsis
06/2019
1Acute Kidney Injury (Acute Renal Failure)
06/2019
1Traumatic Brain Injuries (Traumatic Brain Injury)
01/2019
1Hypoxia (Hypoxemia)
07/2018
1Brain Injuries (Brain Injury)
07/2018
1Carcinoma (Carcinomatosis)
01/2018
1Alopecia (Baldness)
01/2017
1Kyphosis
01/2017
1Premature Aging
01/2017
1Pathologic Processes
10/2016
1Dry Eye Syndromes (Dry Eye Syndrome)
12/2015
1Corneal Injuries
12/2015
1Reperfusion Injury
08/2015
1Acute Erythroblastic Leukemia (Erythroleukemia)
01/2015
1Chromosome Aberrations (Chromosome Abnormalities)
01/2015
1Sarcopenia
02/2014
1Memory Disorders (Memory Loss)
01/2014
1Infections
08/2013
1Pyelonephritis
08/2013
1Bacterial Infections (Bacterial Infection)
08/2013
1Brain Diseases (Brain Disorder)
01/2012
1Obesity
01/2010
1Cataract (Cataracts)
05/2009
1Retinal Dysplasia
05/2009
1Osteoporosis
05/2009
1Lymphoma (Lymphomas)
05/2009
1Hypothermia
05/2009
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2008
1Myocardial Infarction
04/2005

Drug/Important Bio-Agent (IBA)

19AntioxidantsIBA
06/2019 - 05/2009
8Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020 - 05/2009
8PlastoquinoneIBA
01/2019 - 02/2010
4Amyloid (Amyloid Fibrils)IBA
12/2016 - 01/2012
4Proteins (Proteins, Gene)FDA Link
12/2016 - 12/2008
3CationsIBA
01/2018 - 01/2010
2Neuroprotective AgentsIBA
07/2018 - 08/2015
2Mitochondrial DNA (mtDNA)IBA
01/2017 - 01/2015
2RhodaminesIBA
01/2015 - 08/2012
2LipidsIBA
01/2015 - 05/2009
2mitoquinoneIBA
05/2006 - 04/2005
1SenotherapeuticsIBA
01/2020
1plastoquinolIBA
06/2019
1LipopolysaccharidesIBA
06/2019
1Oxygen (Dioxygen)IBA
07/2018
1MitoTEMPOIBA
01/2017
1CarbonIBA
10/2016
1triphenylphosphoniumIBA
10/2016
1HydroquinonesIBA
10/2016
1Ophthalmic Solutions (Eye Drops)IBA
12/2015
1VisomitinIBA
12/2015
1thymoquinoneIBA
08/2015
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2015
1Transforming Growth Factor beta (TGF-beta)IBA
07/2015
1Extracellular Matrix ProteinsIBA
07/2015
1decyltriphenylphosphoniumIBA
05/2015
1HydrocarbonsIBA
01/2015
1Indicators and Reagents (Reagents)IBA
01/2015
1Histones (Histone)IBA
01/2015
1DNA (Deoxyribonucleic Acid)IBA
01/2015
1Cardiolipins (Cardiolipin)IBA
01/2015
1Adenosine Triphosphate (ATP)IBA
01/2015
1SolutionsIBA
01/2015
1Hypromellose DerivativesIBA
01/2015
1Anti-Bacterial Agents (Antibiotics)IBA
08/2013
1decaneIBA
08/2012
1tau Proteins (tau Protein)IBA
01/2012
1PH.3IBA
01/2010
1phenylhydrazoneIBA
01/2010
11-phenyl-3,3-dimethyltriazene (PDT)IBA
05/2006

Therapy/Procedure

3Intraperitoneal Injections
12/2016 - 01/2013
2Therapeutics
01/2020 - 08/2013
1Intravenous Administration
01/2019
1Injections
01/2015
1Radiotherapy
01/2015